一只名叫霍顿、非常有想象力的大象，在一个极为偶然的情况下，听到了一粒在空气中漂浮的灰尘上传来了微弱的求救声，他怀疑就和奥秘的宇宙是一个道理，这粒灰尘上也存在着生命体。

Horton: I meant what I said, and I said what I meant.

Morton: [sighs] An elephant's faithful one hundred percent.

Horton: That's my code, my motto.

大象霍顿：我总是言必行，行必果。

老鼠莫顿：大象都是百分百说话算话的。

大象霍顿：这是我的原则，我的座右铭。

Katie: In my world everyone is a pony, and they all eat rainbows, and poop butterflies.

刺猬（？）凯蒂：在我的世界上，人人都是小马驹，他们吃了彩虹之后就会啪地一下变成蝴蝶。

Morton: Horton, the kangaroo has sent Vlad!

Horton: Vlad? Vlad, Vlad... I know two Vlads. There's the bad Vlad... And then there's bunny Vlad, the one that makes cookies!

Morton: ...Yeah, Horton, she's sending you a bunny with cookies. I think it's safe to say it's the bad Vlad.

Horton: Yeah, good call.

老鼠莫顿：霍顿，袋鼠可是派了弗拉德来了。

大象霍顿：弗拉德？弗拉德，弗拉德……我认识俩弗拉德。有一个坏蛋弗拉德……还有个兔子弗拉德，会做好吃饼干的那个！

老鼠莫顿：……好吧，霍顿，她派了会做饼干的兔子来。我只是觉得说坏蛋弗拉德的话保险一点。

大象霍顿：是耶，主意不错。YouTheme

Horton: And Morton, for being the only one who stood by me. Well not right by me; he hid in the bushes sending me good thoughts. He's small.

Morton: Dude, you are a warrior poet.

大象霍顿：我还要谢谢莫顿，你是一个跟我并肩作战的。好吧，也不是那么并肩来着，他躲在灌木丛里头给我善意的提醒。他很小。

老鼠莫顿：伙计，你还真是个战场诗人。

Horton: All right, I gotta get this speck up to the top of Mount Nool A.S.A.P, whatever that means, probably 'act swiftly, awesome pachyderm'! I mean, how hard can that be? YouTheme

大象霍顿：好吧，我得把这粒微尘送到Nool山上去，A.S.A.P，虽然不知道那是什么意思。大概是说“快跑吧，皮糙肉厚的家伙”！有啥难的咧，是吧？

Narrator: [epilogue] And so, all ended well for both Horton and Who's, and for all in the jungle, even kangaroos. So let that be a lesson to one and to all; a person is a person, no matter how small.

旁白：于是，霍顿和无名氏们都平安无事了，整个丛林，甚至袋鼠也都一团和气。这个故事告诉我和我们所有人，生命就是生命，无论多么渺小。